To continue the thread, what's a transhumanist? My definition: someone who believes that in the not to far future we'll transcend some or all of our current limitations. So, what are the limitations? The most important ones at this point seem to be: health and longevity.

So, by this definition, even if you don't believe in living in a simulation and you don't believe that we'll integrate with computers, you can still be a transhumanist.