| Behavior, gene expression, and biomarkers of physiological ageMost microarray studies of aging animals try to associate gene expression with chronological age: they look for groups of genes that are upregulated or downregulated as we get older. But chronological age is often an imperfect proxy for the quantity we are really interested in – physiological age, or bodily health, which is notoriously difficult to quantify. In the latest issue of Aging Cell, Golden et al. argue that behavior is a useful proxy for physiological age. |
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