Telomerase overexpression slows aging
Expressing telomerase in a wide variety of somatic cells would seem a tempting strategy for lifespan extension. Specifically, telomerase expression could prevent any age-related decline in tissue function can be attributed to decreased regenerative potential. We know why this is a non-starter, of course: What do you call a cell with an unlimited division potential that’s not a stem cell or germ cell? Usually “cancer.” But what if cancer couldn’t form for other reasons?
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