| Calorie restriction prevents age-related damage to mitochondriaA new study has measured the number of abasic sites (AP, referring to apurinic and apyrimidinic) in the mitochondrial genome of young and aged rat brain. AP sites are positions along the DNA backbone where no adenine, guanine, cytosine, or thymine is attached; they are among the most frequent damages to DNA. The authors showed that in normally feeding animals, the number of AP sites increases with age — but calorie restricted (CR) mice did not show such an increase. |
|
|
